
Radiofrequency Ablation (RF) for the treatment of Uterine Fibroids

Uterine fibroids, also known as myomas, are very common benign tumors, especially in women in their 40s and early 50s. Myoblate™ treats uterine fibroids safely and effectively. The procedure is minimally-invasive, using targeted RF ablation to quickly relieve symptoms, slow or stop the growth of fibroids and reduce fibroid volume over time.
What treatment options are available?
There are different kinds of uterine fibroid treatments available, with surgery (hysterectomy and myomectomy) being the most aggressive and medical management therapies (birth control, IUD, tranexamic acid, Gn-RH) being the least invasive approaches for symptom management.
Novel therapeutic options include a non-invasive approach that preserves your uterus, requires no incision, and is done on an outpatient basis.

How does Radiofrequency Ablation work?

The Generator creates RF energy that is safely delivered to the MYOBLATE™ RF Electrode (sometimes called Needle). The heat dispersed at the electrode’s tip destroys the fibroid tissue. It only ablates 70-80% of the fibroid mass to preserve healthy uterine tissue.

By causing coagulative necrosis of the fibroid tissue during the procedure, the denatured cells are dissolved over time. Symptoms are resolved gradually, and the uterine fibroid stops growing. After a year, the fibroid generally shrinks by 60–90%.(1-3)
Depending on the type of fibroids and preferences, the procedure can be done by transcervical approach with abdominal ultrasound guidance
Features & Benefits

- Minimally-invasive
- Uterus preservation (1,2)

- Equipped with Ultrasound Probe Needle Guide
- Precise targeting
- Hyperechoic tip for clear identification

- Fast & simple procedure
- Outpatient procedure
- Rapid recovery (1,2)

- Choose the best approach for each patient with multi-modal approach
- Compatible with existing ultrasound setups

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Low risk of complications (1,2)
- Low recurrence rate (3)
- Repeated procedure is possible

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Reduced blood loss and pain
- Quicker symptom relief than traditional surgical options (1)
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Cho HH, Kim MR, Kim JH. Outpatient multimodality management of large submucosal myomas using transvaginal radiofrequency myolysis. J Minim Invasive Gynecol. 2014 Nov-Dec;21(6):1049-54. doi: 10.1016/j.jmig.2014.04.019. Epub 2014 May 29. PMID: 24882599.
- Kim CH, Kim SR, Lee HA, Kim SH, Chae HD, Kang BM. Transvaginal ultrasound-guided radiofrequency myolysis for uterine myomas. Hum Reprod. 2011 Mar;26(3):559-63. doi: 10.1093/humrep/deq366. Epub 2011 Jan 7. PMID: 21216788.
- Young Lee, Hyun Hee Cho, Jin Hong Kim, Jang Heub Kim, Mee Ran Kim, Young Ok Lew, and SungJin Hwang. Radiofrequency Thermal Ablation of Submucosal Leiomyoma: A Preliminary Report on Health, Symptom, and Quality of Life Outcomes. Journal of Gynecologic Surgery.Dec 2010.227 231.http://doi.org/10.1089/gyn.2009.0101
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